Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 October 2003

Treatment of blood aspiration syndrome with natural surfactant – does it work in neonates?

Ewa Gulczyńska, Agnieszka Zjawiona, Barbara Sobolewska, Marek Nowiczewski, Janusz Gadzinowski

Med Sci Monit 2003; 9(5): 32-35 :: ID: 428687

Abstract

Background: Exogenous surfactant was introduced into treatment of neonatal RDS over 20 years ago.Since that time indications for surfactant were extended to ‘non-RDS ’aetiology.We present three cases of blood aspiration syndrome treated with exogenous surfactant. Material/Methods: Neonates were delivered by emergency cesarean section at Polish Mother ’s Memorial Hospital beceause of pre- mature placental ablation. Mean gestational age was 37.3 weeks,mean birth weight 2766 g (1700 –3450 g).After tracheal suction- ing under direct laryngoscopy infants were intubated and ventilatory support with high respirator settings was started.Mean initial value of Oxygenation Index (OI)was 36.3 and alveolar-to-arterial oxygen gradient (A-a DO 2 )611.7 torr.All patients were treated with natural surfactant.One infant received two boluses,the remaining two were treated with broncho-alveolar surfactant lavage (5 mg phospholipids/mL;15 mL/kg). Results: In patient who received bolus of surfactant blood clots were obtained from respiratory tract with subsequent improvement of ventilation.In neonates treated with lavage a normalization gas exchange was also noticed (after 24 hours OI dropped by 92.1%and A-a DO 2 by 92.3%).Extubation was possible in all three patients with no signs of pulmonary hemorrhage or other side effects associated with surfactant administration. Conclusions: This first data concerning natural surfactant usage in blood aspiration syndrome suggest potential benefits.

Keywords: blood aspiration syndrome, surfactant, newborn infant

Add Comment 0 Comments

Editorial

01 February 2024 : Editorial  

Editorial: Global Health Concerns as Vaccine-Preventable Infections Including SARS-CoV-2 (JN.1), Influenza, Respiratory Syncytial Virus (RSV), and Measles Continue to Rise

Dinah V. Parums

DOI: 10.12659/MSM.943911

Med Sci Monit 2024; 30:e943911

0:00

In Press

01 Feb 2024 : Review article  

Review of the Evaluation of Pulmonary Hypoplasia as an Important Determinant of Clinical Outcomes in Infant...

Med Sci Monit In Press; DOI: 10.12659/MSM.943259  

0:00

19 Feb 2024 : Clinical Research  

Diagnostic Accuracy of Ileocolic Artery and Vein Diameter for Acute Appendicitis

Med Sci Monit In Press; DOI: 10.12659/MSM.943846  

23 Feb 2024 : Clinical Research  

Early Mobilization in Pediatric Critical Care: Exploring the Gap Between Theory and Practice in Saudi Arabia

Med Sci Monit In Press; DOI: 10.12659/MSM.942467  

01 Feb 2024 : Review article  

Enhancing Patient Adherence to Newly-Prescribed Medicine for Chronic Diseases: A Comprehensive Review and C...

Med Sci Monit In Press; DOI: 10.12659/MSM.942923  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750