31 May 2007
Cytogenetic Results of Recurrent Spontaneous Abortions in Turkey
Huseyin Yuce, Ibrahim Tekedereli, Halit ElyasMed Sci Monit 2007; 13(6): CR286-289 :: ID: 484142
Abstract
Background: Recurrent spontaneous abortion is defined as at least three consecutive pregnancy losses, occuring in 10% of all pregnancies. In the etiology of recurrent spontaneous abortion, a wide variety of abnormalities, such as anatomic, endocrinologic, and genetic abnormalities, has been reported. The aim of this study was to compare karyotyping results of couples with recurrent spontaneous abortions. This may contribute to elucidating the genetic basis of this condition and warn physicians of the cytogenetic abnormalities in cases with recurrent spontaneous abortions.
Material/Methods: The cytogenetic results of patients with at least two abortions referred to Firat (Euphrates) University, College of Medicine, Department of Medical Biology and Genetics in the six-year period between 2000–2005 were reviewed retrospectively.
Results: Of a total of 421 couples (842 patients), 23 men (2.73%) and 8 women (0.95%) had abnormal karyotypes. Balanced and unbalanced karyotypes and polymorphisms had rates of 1.06%, 0.71%, and 1.9%, respectively, the total rate being 3.68%.
Conclusions: These data show that cytogenetic evaluation is necessary for an accurate approach to elucidating the causes of recurrent spontaneous abortion, and physicians should also be careful of the diversity of chromosomal abnormalities that play important roles in the etiology of recurrent spontaneous abortion.
Keywords: Abortion, Habitual - pathology, Turkey, Pregnancy, Karyotyping, Chromosomes, Human - genetics, Chromosomes, Human - genetics, Turkey, Pregnancy, Karyotyping, Abortion, Habitual - pathology
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
06 Mar 2024 : Clinical Research
Prevalence and Variation of Medical Comorbidities in Oral Surgery Patients: A Retrospective Study at Jazan ...Med Sci Monit In Press; DOI: 10.12659/MSM.943884
08 Mar 2024 : Clinical Research
Evaluation of Foot Structure in Preschool Children Based on Body MassMed Sci Monit In Press; DOI: 10.12659/MSM.943765
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952