Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

02 March 1998

Influence of continuous positive airway pressure (CPAP) on the left ventricular function, in patients with obstructive sleep apnoea syndrom (OSAS)

Ryszarda Chazan, Maria Jakubowska-Najniger, Elżbieta Chazan-Polanowska, Tadeusz Przybyłowski, Danuta Liszewska-Pfeifer, Wacław Droszcz

Med Sci Monit 1998; 4(2): CR250-254 :: ID: 502588

Abstract

The aim of this study was to evaluate left ventricular function in patients with OSAS and arterial hypertension following the use of n-CPAP. Twenty-two patients with (OSAS) obstructive sleep apnoea syndrome were divided into two groups: one group comprised patients with OSAS and without arterial hypertension, the other, patients with OSAS and hypertension. The influence of CPAP (continuous positive airway pressure) on left ventricular function was evaluated using 2D and Doppler echocardiography. The systolic left ventricular function (ejection fraction) was normal in all patients. At the beginning of this study both groups demonstrated a decrease in peak mitral flow velocity during early diastole E (m/sec), an increase of atrio-systolic contraction A (m/sec), an increase in E/A and a prolonged isovolemic relaxation time (IVRT). After three months treatment with CPAP, an increase in the E/A, ratio of 1.38±0.23m/sec vs 0.98±0.28 (p<0.05) and a reduction in IVRT, of 79.0±6.8msec vs 91.3±6.3 (p<0.05) in the second group (patients with OSAS and hypertension) could be seen. In the first group (patients with OSAS and without hypertension) we only observed a statistically significant reduction in IVRT, 77.8±5.4 vs 83.7±5.15 msec p<0.05.

Keywords: CPAP (continuous positive airway pressure), OSAS (obstructive sleep apnoea syndrome), Echocardiography

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750