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13 June 2022: Database Analysis

Retrospective Study from a Single Center to Identify Risk Factors Associated with Reinfection in Patients Undergoing 2-Stage Revision Surgery for Periprosthetic Joint Infection

Bingshi Zhang ABCE , Zeming Liu CE , Sikai Liu BC , Bo Liu BC , Mengnan Li B , Wenao Li E , Yongtai Han ABCDE*

DOI: 10.12659/MSM.936973

Med Sci Monit 2022; 28:e936973

Table 2 Results of hematological, bacteriological, and laboratory examinations of patients with periprosthetic joint infection undergoing 2-stage hip revision surgery.

Patient characteristicsInfection recurrence (n=25)Infection nonrecurrence (n=330)P
CRP (mg/L)32.63±14.5926.70±11.590.002*
Albumin (g/L)32.37±8.2536.01±7.410.029*
Globulin (g/L)29.83±6.1924.37±5.870.004*
Albumin/globulin1.12±0.291.49±0.36*
Glucose
7251#
 5.6–11.2846
 >11.21033
Hemoglobin (g/L)119.56±19.31121.72±17.680.827*
ESR (mm/min)52.54±11.5350.71±16.370.392*
Fibrinogen (g/L)3.95±0.883.89±0.970.722*
D-dimer (mg/ml)0.91±0.370.86±0.320.109*
Platelet count341.70±99.65327.23±85.820.510*
MRI findings
 Negative findings2157#
 Only lamellated hyperintense synovitis873
 Only soft tissue edema977
 Lamellated hyperintense synovitis and soft tissue edema623
Allogeneic blood transfusion
 No131640.824#
 Yes12166
Infectious bacteria
Negative458#
 G+ bacteria19257
 G− bacteria215
Antibiotic-resistant bacteria
 Yes8630.120#
 No17267
Antibiotics used regularly (≥3 weeks)
 No6770.939#
 Yes19253
Time of remission (days)28.04±10.3626.14±11.950.602*
Spacer with antibiotics
 No51010.264#
 Yes20229
Time interval between prosthetic resection and hip revision (months)6.87±2.497.02±3.170.291*
CRP – C-reactive protein; ESR – erythrocyte sedimentation rate.
* Mann-Whitney U test;
# Chi-square test.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750