04 January 2022>: Animal Study
Activation of α7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 Pathway
Kun Cao 12BCEF , Jie Xiang 13CF , Yang-Ting Dong 34BCD , Yi Xu 13CD , Zhi-Zhong Guan 134ADG*DOI: 10.12659/MSM.933978
Med Sci Monit 2022; 28:e933978
Figure 2 Absence of any significant histopathological changes in different regions of the hippocampus of the APP/PS1 mice at 6 or 10 months of age. (A) the APP/PS1 mice at 6 months of age. (B) the APP/PS1 mice at 10 months of age. WT – wild-type; Hippo – hippocampus; CA1/3 – Cornu Ammonis area 1/3; DG – dentate gyrus. Magnification: Hippocampus, 40×; CA1, CA2, DG regions, 200×.