02 August 2021>: Meta-Analysis
Association Between Gene Polymorphisms and Risk of Preeclampsia: Systematic Review and Meta-Analysis
Manni Sun BE , Hui Jiang BF , Tao Meng AF , Peiyan Liu BC , Haiying Chen ACG*DOI: 10.12659/MSM.930438
Med Sci Monit 2021; 27:e930438
Table 3 Main results for pooled ORs in the meta-analysis.
Genetic model | Test of association | Test of heterogeneity | Test of publication bias (Egger) | Type of model | ||||
---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | I2 (%) | P | T | P | ||
G vs A | 0.96 | 0.51–1.78 | 0.887 | 67.9 | 0.014 | 1.28 | 0.289 | Random |
GG vs AA | 1.22 | 0.38–3.90 | 0.740 | 0.0 | 0.438 | −1.53 | 0.225 | Fixed |
GG vs GA | 1.18 | 0.32–4.34 | 0.802 | 0.0 | 0.814 | −0.53 | 0.630 | Fixed |
GG+GA vs AA | 0.94 | 0.53–1.67 | 0.826 | 59.8 | 0.041 | 1.40 | 0.256 | Random |
GG vs GA+AA | 1.22 | 0.38–3.93 | 0.743 | 0.0 | 0.479 | −1.40 | 0.255 | Fixed |
T vs C | 1.07 | 0.48–2.38 | 0.871 | 71.5 | 0.015 | 0.87 | 0.474 | Random |
TT vs CC | 1.08 | 0.03–4.63 | 0.922 | 17.8 | 0.296 | −40.8 | 0.016 | Fixed |
TT vs TC | 0.82 | 0.15–4.47 | 0.818 | 0.0 | 0.727 | −2.17 | 0.275 | Fixed |
TT+TC vs CC | 1.07 | 0.50–2.29 | 0.854 | 65.9 | 0.032 | 0.95 | 0.441 | Random |
TT vs TC+CC | 1.05 | 0.24–4.57 | 0.953 | 8.7 | 0.334 | −41.69 | 0.015 | Fixed |