09 February 2022: Clinical Research
A Risk Prediction Model for Prolonged Length of Stay in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Retrospective Study of 225 Patients in a Single Center in Kunming, China
Lifen Yang 1ABCDEFG* , Meihua Li 1BCD , Jingkui Shu 2BCD , Yanxia Yang 1BCD , Qian Huang 3BCDDOI: 10.12659/MSM.934392
Med Sci Monit 2022; 28:e934392
Table 3 Differences in characteristic changes between the fourth and first day.
| Variable | Total (n=225) | Group | Statistic | P | |
|---|---|---|---|---|---|
| LOS ≤7 days (n=73) | LOS >7 days (n=152) | ||||
| Blood routine examination | |||||
| ΔWBC (10/L), mean±SD | −0.87 (−2.42, 0.32) | −1.01 (−2.60, 0.16) | −0.83 (−2.37, 0.34) | Z=−0.443 | 0.658 |
| ΔRBC (10/L), mean±SD | −0.14 (−0.43, 0.19) | −0.13 (−0.46, 0.23) | −0.15 (−0.42, 0.19) | Z=0.176 | 0.860 |
| ΔPCV, mean±SD | −0.01 (−0.04, 0.02) | −0.01 (−0.03, 0.02) | −0.02 (−0.04, 0.01) | Z=1.112 | 0.266 |
| ΔHb (g/L), mean±SD | −3.00 (−11.00, 6.00) | −3.00 (−11.00, 6.00) | −2.00 (−11.00, 6.00) | Z=−0.107 | 0.915 |
| ΔPLT (10/L), M(Q, Q) | −3.00 (−27.00, 21.00) | −10.00 (−40.00, 20.00) | −2.00 (−22.50, 21.50) | Z=−1.433 | 0.152 |
| ΔNEUT (10/L), M(Q, Q) | −0.89 (−2.44, 0.26) | −0.42 (−2.53, 0.50) | −1.03 (−2.43, 0.11) | Z=0.978 | 0.328 |
| ΔLY (10/L), M(Q, Q) | 0.20 (−0.10, 0.60) | 0.20 (−0.20, 0.40) | 0.20 (0.00, 0.60) | Z=−1.236 | 0.217 |
| Blood gas analysis | |||||
| ΔpH, mean±SD | 0.01 (−0.03, 0.05) | 0.00 (−0.04, 0.03) | 0.01 (−0.03, 0.05) | Z=−1.365 | 0.172 |
| ΔPaCO (mmHg), mean±SD | −1.00 (−7.00, 5.00) | 0.00 (−5.00, 4.00) | −1.00 (−8.00, 5.50) | Z=0.209 | 0.834 |
| ΔPaO/FiO (mmHg), M(Q, Q) | 26.00 (5.00, 57.00) | 20.00 (5.00, 46.00) | 32.00 (7.00, 59.50) | Z=−1.401 | 0.161 |
| ΔHCO (mmol/L), mean±SD | 0.10 (−3.10, 2.80) | 0.10 (−2.70, 2.40) | 0.10 (−3.25, 3.05) | Z=−0.124 | 0.902 |
| ΔBE (mmol/L), M(Q, Q) | 0.00 (−2.90, 2.60) | −0.20 (−2.90, 2.30) | 0.05 (−2.85, 2.80) | Z=−0.265 | 0.791 |
| Infection markers test, M(Q, Q) | |||||
| ΔCRP (mg/L) | −2.50 (−22.24, 0.70) | −5.27 (−32.18, 0.12) | −1.83 (−17.95, 1.09) | Z=−1.633 | 0.102 |
| ΔPCT (μg/L) | −0.01 (−0.05, 0.01) | −0.02 (−0.09, 0.00) | −0.01 (−0.04, 0.01) | Z=−1.833 | 0.067 |
| ΔAmyloid (mg/L) | −75.40 (−167.70, −18.80) | −48.90 (−153.57, −11.41) | −86.05 (−173.34, −21.32) | Z=1.675 | 0.094 |
| ΔIL-6 (pg/mL) | −3.80 (−17.60, 1.20) | −4.20 (−18.40, 1.40) | −3.65 (−17.55, 0.90) | Z=−0.054 | 0.957 |
| LOS – length of stay; WBC – white blood cell; RBC – red blood cell; PCV – packed-cell volume; Hb – hemoglobin; PLT – platelet; NEUT – neutrophil; LY – lymphocyte; PaCO – partial arterial carbon dioxide pressure; PaO/FiO – the ratio of partial arterial oxygen pressure to the fraction of inspired oxygen; BE – base excess; CRP – C-reactive protein; PCT – procalcitonin; SD – standard deviation; M(Q,Q) – median and quartile; n(%) – the number of cases and the constituent ratio; Δ – changes between the fourth and first day of hospitalization. | |||||