13 February 2022>: Clinical Research
Gas Chromatography and Flame-Ionization Detection of Non-Cholesterol Sterols as Indicators of Cholesterol Absorption and Synthesis in 158 Chinese Individuals with Normolipidemia, Hyperlipidemia, and Familial Hypercholesterolemia
Zhi-Zhao Li 1DE* , Qi-Hui Wang 2C , Yang Liu 2C , Lv-Ya Wang 3A , Zhen-Qiu Yu 3A , Qiong Huang 4B , Jing Zhang 5BDOI: 10.12659/MSM.934471
Med Sci Monit 2022; 28:e934471
Table 3 Results of multifactorial regression analysis.
Item | B | SE | Wald | Sig. | Exp (B) | 95% CI EXP (B) | |
---|---|---|---|---|---|---|---|
LL | UL | ||||||
Sex | 0.509 | 1.021 | 0.248 | 0.618 | 1.663 | 0.225 | 12.312 |
Age (year) | 0.025 | 0.065 | 0.142 | 0.706 | 1.025 | 0.902 | 1.165 |
BMI (kg/m) | 0.005 | 0.109 | 0.002 | 0.965 | 1.005 | 0.812 | 1.244 |
TG (mmol/L) | 5.919 | 1.415 | 17.497 | 372.170 | 23.238 | 5960.466 | |
TC (mmol/L) | 4.384 | 1.419 | 9.552 | 80.197 | 4.973 | 1293.413 | |
HDL-C | −0.758 | 1.109 | 0.467 | 0.494 | 0.468 | 0.053 | 4.119 |
LDL-C | −0.697 | 1.318 | 0.280 | 0.597 | 0.498 | 0.038 | 6.593 |
FPG (mmol/L) | 0.910 | 0.540 | 2.842 | 0.092 | 2.485 | 0.862 | 7.164 |
SBP (mmHg) | −0.028 | 0.060 | 0.227 | 0.634 | 0.972 | 0.864 | 1.093 |
DBP (mmHg) | −0.007 | 0.081 | 0.007 | 0.933 | 0.993 | 0.847 | 1.164 |
Squalene (%) | −0.081 | 0.084 | 0.935 | 0.334 | 0.922 | 0.782 | 1.087 |
Desmosterol (%) | −35.604 | 13.950 | 6.514 | ||||
Lathosterol (%) | 0.794 | 0.781 | 1.034 | 0.309 | 2.212 | 0.479 | 10.211 |
Campesterol (%) | −0.457 | 0.883 | 0.268 | 0.605 | 0.633 | 0.112 | 3.572 |
Stigmasterol (%) | −0.413 | 1.689 | 0.060 | 0.807 | 0.662 | 0.024 | 18.136 |
Sitosterol (%) | 0.460 | 0.989 | 0.216 | 0.642 | 1.584 | 0.228 | 11.006 |
Constant | −26.228 | 8.761 | 8.963 | 0.003 | |||
BMI – body mass index; HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; TG – triglycerides; TC – total cholesterol; FPG – fasting plasma glucose; SBP – systolic blood pressure; DBP – diastolic blood pressure; FH – familial hypercholesterolemia; SE – standard error. |