16 March 2022: Animal Study
A New Target of the Four-Herb Chinese Medicine for Wound Repair Promoted by Mitochondrial Metabolism Using Protein Acetylation Analysis
Zhongzhi Zhou 1ABCDEFG* , Li Chen 23ABCDEFG* , Yuxin Su 4ABCDEF* , Meirong Li 3CE , Lingzhi Zhong 3BCD , Liangying Liao 1DEF , Yarong Ding 2CEF , Mulin Liu 2CDE , Zhonghang Yuan 2CDE , Wei Wang 2CEF , Xinyu Huang 2BC , Xiuna Fang 2AEG , Xiaobing Fu 3AEG , Wenjun He 3ADEF , Qian Hou 3ABFGDOI: 10.12659/MSM.934816
Med Sci Monit 2022; 28:e934816
Table 4 GO annotation for upregulated and downregulated acetylated proteins.
| GO terms level 1 | GO terms level 2 | No. of upregulated acetylated proteins | No. of downregulated acetylated proteins |
|---|---|---|---|
| Cellular process | 78 | 28 | |
| Single-organism process | 71 | 24 | |
| Metabolic process | 56 | 17 | |
| Biological regulation | 54 | 21 | |
| Multicellular organismal process | 49 | 21 | |
| Response to stimulus | 44 | 20 | |
| Developmental process | 39 | 15 | |
| Organelle | 86 | 27 | |
| Cell | 85 | 30 | |
| Extracellular region | 63 | 24 | |
| Macromolecular complex | 51 | 18 | |
| Membrane | 50 | 13 | |
| Binding | 75 | 31 | |
| Catalytic activity | 43 | 12 | |
| Structural molecule activity | 15 | 3 | |
| Transporter activity | 7 | 3 |