20 April 2022>: Clinical Research
Effects of Interaction Between Gestational Hypertension and History of Preterm Birth on the Risk of Preterm Birth: An Analysis Based on the National Vital Statistics System Database
Xiaoqin Cao 1AE , Daoming Zu 2BCD , Yang Liu 1AE*DOI: 10.12659/MSM.935094
Med Sci Monit 2022; 28:e935094
Table 3 Logistic regression analyses of the effects of the interaction between gestational hypertension and history of preterm birth on preterm birth.
GH | HPB | Model 1 | Model 2 | Model 3 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | ||
No | No | Ref | Ref | |||||||
No | Yes | 3.523 | 3.467–3.581 | 3.277 | 3.224–3.331 | 3.199 | 3.143–3.255 | |||
Yes | No | 2.725 | 2.695–2.756 | 2.703 | 2.673–2.734 | 2.666 | 2.633–2.699 | |||
Yes | Yes | 6.638 | 6.388–6.897 | 6.117 | 5.885–6.358 | 6.095 | 5.847–6.352 | |||
RERI | 1.389 (1.129–1.649) | 1.143 (0.900–1.385) | 1.222 (0.965–1.479) | |||||||
AP | 0.209 (0.178–0.241) | 0.187 (0.154–0.219) | 0.201 (0.167–0.235) | |||||||
S | 1.327 (1.266–1.391) | 1.287 (1.226–1.351) | 1.317 (1.250–1.387) | |||||||
OR – odds ratio; CI – confidence interval; Ref – reference ;GH – gestational hypertension; HPB – history of preterm birth; RERI – relative excess risk of interaction; AP – attributable proportion of interaction; S – synergy index. univariate analysis; the variables including age, race, and educational attainment of mother and father were corrected; adjusted variables included age, race, and educational attainment regarding father and mother, pre-pregnancy BMI, weight gain during pregnancy, cigarette smoking before and during pregnancy, method of delivery, number of fetus, payment source for delivery, previous cesarean, pre-pregnancy diabetes, gestational diabetes, infection, eclampsia, sex of infant. |