12 May 2022>: Clinical Research
Retrospective Study from a Single Center to Evaluate the Association Between Sex and Serum Uric Acid Levels in 950 Patients with Atrial Fibrillation
Xia Zhong 1ABCE , Huachen Jiao 2BDFG* , Dongsheng Zhao 1BCD , Jing Teng 1ADFDOI: 10.12659/MSM.935273
Med Sci Monit 2022; 28:e935273
Table 4 Association between levels of serum uric acid and metabolic factors in patients with paroxysmal atrial fibrillation by sex.
Variable | Male patients (n=180) | Female patients (n=152) | ||||||
---|---|---|---|---|---|---|---|---|
<5.5 mg/dL | 5.5–6.5 mg/dL | >6.5 mg/dL | P value | <4.2 mg/dL | 4.2–5.0 mg/dL | >5.0 mg/dL | P value | |
Number, n | 80 | 46 | 54 | 45 | 40 | 67 | ||
Creatinine, μmoI/L | 71.15±17.60 | 82.59±18.87 | 88.28±31.34 | 0.005* | 54.36±13.43 | 68.50±46.35 | 86.88±38.16 | * |
AST, U/L | 25.46±24.23 | 28.11±27.00 | 29.28±37.87 | 0.243 | 20.76±9.39 | 20.50±7.58 | 23.19±14.47 | 0.402 |
ALT, U/L | 27.75±30.42 | 25.30±28.85 | 27.57±24.08 | 0.885 | 17.38±9.63 | 18.85±11.89 | 20.19±15.92 | 0.547 |
APOA1, g/L | 1.05±0.31 | 1.07±0.20 | 1.03±0.24 | 0.754 | 1.18±0.27 | 1.19±0.25 | 1.18±0.30 | 0.981 |
APOB, g/L | 0.84±1.02 | 0.79±0.21 | 0.83±0.26 | 0.927 | 0.76±0.20 | 0.84±0.27 | 0.87±0.30 | 0.100 |
ALB, mg/L | 35.72±5.40 | 38.53±4.62 | 38.43±4.58 | 0.001* | 37.20±5.57 | 37.77±4.48 | 38.16±4.31 | 0.579 |
PAB, mg/L | 172.15±68.57 | 209.17±66.29 | 207.91±60.42 | 0.001* | 172.82±68.04 | 193.65±53.31 | 195.67±59.44 | 0.124 |
TG, mmol/L | 0.99±0.43 | 1.26±0.85 | 1.14±0.52 | 0.043* | 1.14±0.58 | 1.64±2.51 | 1.30±0.71 | 0.251 |
TC, mmol/L | 3.78±0.93 | 4.16±0.89 | 4.14±1.16 | 0.049* | 4.20±1.07 | 4.63±1.39 | 4.54±1.29 | 0.235 |
LDL-C, mmol/L | 2.16±0.69 | 2.49±0.72 | 2.64±0.92 | 0.001* | 2.51±0.88 | 2.67±1.09 | 2.76±1.26 | 0.509 |
HDL-C, mmol/L | 1.06±0.40 | 1.01±0.21 | 0.96±0.22 | 0.190 | 1.13±0.34 | 1.18±0.33 | 1.14±0.40 | 0.800 |
Data are presented as mean±SD. AST – aspartate aminotransferase; ALT – alanine aminotransferase; APOA1 – apolipoprotein A1; APOB – apolipoprotein B; ALB – albumin; PAB – prealbumin; TG – triglyceride; TC – total cholesterol; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol. * Statistically significant value ( |