16 June 2022: Clinical Research
Renal Manifestations in Inflammatory Bowel Disease: A Cohort Study During the Biologic Era
Mevlut Tamer Dincer 1ABCDEF , Zeynep Toker Dincer 2BCE* , Oguz Kagan Bakkaloglu 3CEF , Serkan Feyyaz Yalin 4BE , Sinan Trabulus 1ADE , Aykut Ferhat Celik 3AE , Nurhan Seyahi 1CDE , Mehmet Riza Altiparmak 1ACDEDOI: 10.12659/MSM.936497
Med Sci Monit 2022; 28:e936497
Table 1 Demographic characteristics and comorbidities of inflammatory bowel disease patients with renal involvement and controls.
| Crohn’s disease | Ulcerative colitis | |||||
|---|---|---|---|---|---|---|
| Patients with renal involvement (n=55) | Control group (n=45) | p | Patients with renal involvement (n=50) | Control group (n=60) | p | |
| 45.7±12.6 | 42.1±12.1 | 0.116 | 51.5±15.0 | 46.9±12.6 | 0.084 | |
| 58.2 | 60.0 | 0.854 | 60.0 | 46.7 | 0.163 | |
| Primary school | 38.5 | 22.7 | 30.4 | 43.1 | ||
| Secondary school | 11.5 | 13.6 | 0.340 | 13.0 | 17.2 | 0.378 |
| High school | 30.8 | 45.5 | 32.6 | 20.7 | ||
| University or higher | 19.2 | 18.2 | 23.9 | 19.0 | ||
| 58.2 | 73.3 | 0.114 | 46.0 | 40.0 | 0.526 | |
| 10.9 | 8.9 | 0.738 | 12.0 | 13.3 | 0.835 | |
| ,* | 12.7 | 8.9 | 0.542 | 20.0 | 6.7 | |
| Diabetes mellitus | 1.8 | 2.2 | 0.700 | 14.0 | 3.3 | |
| Hypertension | 7.3 | 4.4 | 0.554 | 28.0 | 6.7 | |
| Hyperlipidemia | 16.3 | 22.2 | 0.457 | 36.0 | 31.7 | 0.631 |
| Hyperuricemia | 5.5 | 2.2 | 0.411 | 6.0 | 1.7 | 0.226 |
| * Calculated for NSAID use. Significant p values are written in bold. | ||||||