10 August 2022>: Clinical Research
A Retrospective Study from a Single Center to Identify Hematological Factors that Distinguish Between Patients with Colorectal Carcinoma and Colorectal Adenoma
Jun Huang 12AE , Pingping Xu 3BCD , Youxiang Chen 4AE*DOI: 10.12659/MSM.936745
Med Sci Monit 2022; 28:e936745
Table 6 The performance of the prediction model in training and testing sets.
Patients grouped into CRC and colorectal adenoma | Patients grouped into stage I, II, and III CRC and colorectal adenoma | Patients grouped into poorly differentiated CRC, moderately and well-differentiated CRC, and colorectal adenoma | ||||
---|---|---|---|---|---|---|
Training set | Testing set | Training set | Testing set | Training set | Testing set | |
AUC (95% CI) | 0.864 (0.834–0.895) | 0.848 (0.800–0.896) | 0.818 (0.799–0.838) | 0.806 (0.775–0.836) | 0.857 (0.838–0.876) | 0.829 (0.797–0.860) |
Accuracy (95% CI) | 0.808 (0.777–0.840) | 0.777 (0.726–0.828) | 0.746 (0.729–0.764) | 0.733 (0.706–0.760) | 0.822 (0.805–0.840) | 0.788 (0.759–0.817) |
Sensitivity (95% CI) | 0.852 (0.816–0.888) | 0.812 (0.752–0.873) | 0.745 (0.710–0.780) | 0.727 (0.672–0.781) | 0.762 (0.728–0.796) | 0.715 (0.660–0.770) |
Specificity (95% CI) | 0.738 (0.681–0.795) | 0.719 (0.629–0.809) | 0.747 (0.727–0.767) | 0.736 (0.704–0.767) | 0.853 (0.832–0.873) | 0.824 (0.791–0.857) |
PPV (95% CI) | 0.840 (0.803–0.877) | 0.828 (0.769–0.887) | 0.495 (0.462–0.528) | 0.478 (0.429–0.528) | 0.721 (0.686–0.756) | 0.670 (0.615–0.726) |
NPV (95% CI) | 0.754 (0.698–0.811) | 0.697 (0.606–0.787) | 0.898 (0.882–0.913) | 0.890 (0.865–0.914) | 0.877 (0.859–0.896) | 0.853 (0.821–0.884) |
AUC – area under the curve; CI – confidence interval; PPV – positive predictive value; NPV – negative predictive value; CRC – colorectal cancer. |